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.Now researchers at Stanford University believe they may have hit on a reason why a having a coffee or tea break is so good for us.Inflammation also plays a key role in many other diseases, the research study said.What weve shown is a correlation between caffeine consumption and longevity. And weve shown more rigorously, in laboratory tests, a very plausible mechanism for why this might be so.The study was published in Nature Medicine.The authors found that in an ongoing study following participants aged 20-30, and another group of people aged 60, those who tended to drink more caffeinated beverages had lower levels of inflammatory compounds in their blood. It helps to block chemicals in the blood that promote inflammation, they say. Tests on the blood of people fewer of the chemicals linked to inflammation - were found to have more caffeine in their bloodstream.Further investigation revealed that they, as might be expected, drank more coffee than their peers.Caffeine, the ingredient that gives coffee, tea and some fizzy drinks a lift blocks chemicals in our blood that promote inflammation. Many studies have shown this association. A chemical found in chocolate, theobromine, was also found to have an anti-inflammatory effect, although not as pronounced as caffeine. Drinking coffee and tea may help people to live longer by reducing chemicals in the blood that can trigger heart disease, researchers have found.US scientists believe theyve found the answer - and its to do with caffeine.David Furman of the Stanford Universitys Institute for Immunity, Transplantaion and Infection said: More than 90 per cent of all noncommunicable diseases of aging are associated with chronic inflammation. It also found more platelets platelets, which make blood more likely to clot. The key chemical combated by caffeine is called Interleukin-1-beta.London: Why do coffee drinkers tend to have a longer life? The finding that coffee drinkers tend to live longer than people who abstain has long puzzled scientists. Inflamed blood vessels are more likely to become stiffer - a risk factor for heart disease.Dr Furmann added: Its also well known that caffeine intake is associated with longevity. China Insulin assembly machine for sale It also led to immune cells - white blood cells that fight infection and - clogging the animals kidneys. When injected into mice, IL-1-Beta led to massive systemic inflammation, along with high blood pressure.His colleague Mark Davis added: Our findings show that an underlying inflammatory process, which is associated with aging, is not only driving cardiovascular disease but is, in turn, driven by molecular events that we may be able to target and combat. Weve found a possible reason for why this may be so.Further tests in the laboratory in human cell cultures found that caffeine had an active role in combating the chemicals that trigger inflammation.Dr Davis said: That something many people drink - and actually like to drink - might have a direct benefit came as a surprise to us. ادامه مطلب
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New advances are allowing researchers to study cancer via the bloodstream where tumor cells shed small, detectable pieces of their DNA, according to researchers.Although tumor biopsies are generally used to assess changes in a cancer's DNA, blood samples can do the same thing, according to the study presented at the annual meeting of the American Society of Clinical Oncology.And because genetic changes in cancer DNA occur even before tumor growth becomes evident in a scan, blood samples can help health professionals adjust a patient's treatment sooner. Chicago, United States: Blood samples can be just as effective as invasive tissue biopsies in monitoring cancer and can help doctors better prescribe treatment, a study revealed on Saturday.." These findings suggest that analysis of shed tumor DNA in patient blood, also known as a liquid biopsy, can be a highly informative, minimally-invasive alternative when a tissue China Vaccine needle assembly machine for sale biopsy is insufficient for genotyping or cannot be obtained safely," said study presenter Philip Mack, professor and director of molecular pharmacology at the University of California Davis Comprehensive Cancer Center.The study was carried out using blood samples from more than 15,000 patients and 50 types of tumors.Blood tests can also provide a more comprehensive sample of a tumor's DNA since biopsy tissue comes from only one part of a tumor and therefore may not provide a sample of the changing DNA."Having a good, reliable option beyond a tumor biopsy could have a major impact on our ability to select the right therapy for the right patient," said Sumanta Kumar Pal, a medical oncologist at the City of Hope cancer center in California, who was not involved in the research.By assessing this DNA doctors can "monitor changes in the cancer as it evolves over time, which can be critical when patients and physicians are discussing treatment options for continued tumor control," according to a preview of the study.Researchers used a test by California-based Guardant Health, which looks for mutations in 70 cancer-related genes." The fact that genomic mutations vary not only patient to patient but also change over time has been a constant challenge in cancer treatment, especially in the precision medicine era" he said.And blood samples allow doctors to do so without resorting to an involved, surgical tumor biopsy, said researchers on the study, one of the largest ever conducted on cancer genomics.The study was carried out using blood samples from more than 15,000 patients and 50 types of tumors. ادامه مطلب
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